ABBDCCCholesterolPregnenoloneProgesterone11-DeoxycorticosteroneCorticosterone18-OH-CorticosteroneAldosterone17-OH Pregnenolone17-OH Progesterone11-DeoxycortisolCortisolDehydroepiandrosteroneAndrosteroneTestosteroneMineralocorticoidGlucocorticoidAndrogenA = cholesterol side-chain cleavage (3beta-hydroxydehydrogenase and delta-5, delta-4-isomerase)B = 17-hydroxylaseC = 17,20-lyaseD = 11beta-hydroxylase 20,22D3HSD21OH11OH17OH17OH18OH18HSD21OH11OH17,20D17,20D3HSD17HSDAromataseAromatase17HSDHOCholesterolHOC=OCH3PregnenoloneOC=OCH3ProgesteroneOC=OCH2OH11-DeoxycorticosteroneOHOC=OCH2OHCorticosteroneHOC=OCH3OH17α-HydroxypregnenoloneOC=OCH3OH17α-HydroxyprogesteroneOC=OCH2OHOH11-DeoxycortisolOHOH2CHOC=OCH2OH18-HydroxycorticosteroneHOODehydroepiandrosteroneOO4-AndrostenedioneOHOC=OCH2OHOHCortisolOOHCHOC=OCH2OHAldosteroneOOHTestosteroneHOOOestroneHOOHOestradiol-17βGlucocorticoidsMineralocorticoidsOestrogensAndrogens